Tag Archives: Mild Cognitive Impairment (MCI)

When Memory Loss is not Alzheimer’s or Dementia: Vitamin B Deficiencies

We thought it would be useful to expand on other causes of memory loss that are not directly linked to Alzheimer’s disease or other types of dementia. A surprisingly common source of memory loss symptoms is a Vitamin B-12 deficiency. Vitamin B-12 intake is necessary for healthy brain function and maintaining intact myelin sheaths (the […]

The Coming Ethical Quagmire with Brain Imaging Tests

With sophisticated brain imaging tests now making their way out of research labs or clinical trials, and into the doctor’s office, both patients and physicians will have to confront some important ethical and legal questions on how these tests are used. That’s the message from a seminar on amyloid imaging, hosted by the American Academy […]

Is the Amyloid Hypothesis Dead Wrong?

After the disaster known as bapineuzumab Phase III, I think it’s time to seriously question whether clearing amyloid beta deposits from the brain has any therapeutic benefit to Alzheimer’s patients. The bapi Phase III results speak with a resounding “No”. We are still awaiting Phase III results from Eli Lilly’s solanezumab, but the current prognosis […]

Detecting Alzheimer’s Disease 20 Years Before Symptoms Appear

A research team at Washington University School of Medicine just published the results of a study that looked at a number of cognitive changes and biomarkers that can be used to predict the risk of Alzheimer’s Disease long before symptoms appear – in some cases up to 20 years before symptom onset. The study, published […]

New Progress on a Blood Test for Alzheimer’s Disease

The PLoS ONE science journal published an interesting study performed by the Brain and Aging Research Program at the University of New South Wales in Sydney, Australia. The study sampled apolipoprotein levels in blood samples from over 600 older adults participating in the ongoing Sydney Memory and Aging Study. Apolipoproteins are proteins that transport cholesterol […]

CANTABMobile for Memory and Dementia Screening

Cambridge Cognition announced the general release of a new iPad application for the detection of early memory impairment that is common in Alzheimer’s disease and other forms of dementia. As we reported last September, the iPad application (named CANTABmobile) is based on the Cantab PAL test, a visual working memory test. The CANTABmobile memory test […]

Using Insulin Spray for Alzheimer’s Symptoms

The US government announced additional funding this week for Alzheimer’s prevention and research, including $8 million to test an insulin nasal spray for treating Alzheimer’s disease. The funding was announced as part of the National Plan to Address Alzheimer’s Disease, also known as NAPA 2025. This is an important and useful step to validate an […]

Testing for Mild Cognitive Impairment (MCI)

What is Mild Cognitive Impairment? Mild Cognitive Impairment, or MCI, is an intermediate stage condition between normal cognitive functioning and Alzheimer’s disease or other types of dementia: Signs of MCI include a “change in cognition” — this typically means memory problems, but it can also include planning and reasoning skills that could negatively affect higher […]