Posts Tagged ‘biomarkers’

Merck Advances BACE Inhibitor Trial for Alzheimer’s Disease

16th January 2014 by Christian Elliott Comments Off

Merck announced last month that it is moving ahead with MK-8931, an experimental BACE inhibitor drug designed to slow the production of amyloid beta protein in the brain, one of the hallmarks of Alzheimer’s disease. Beta secretase (BACE) inhibitors work by interfering with the process that creates amyloid beta protein in the first place, in […]

Using Blood Protein Markers for Brain Health Screening

6th August 2013 by Christian Elliott Comments Off

Can a simple blood test be possible to screen for Alzheimer’s disease and other brain conditions? New research discussed at the Alzheimer’s Association International Conference (AAIC) last month suggests that reliable, low cost blood serum analysis for brain biomarkers is a possibility within the next decade or so. Blood tests are an attractive screening option […]

Should Medicare Cover the Cost of Brain Imaging Tests for Alzheimer’s Diagnosis?

16th July 2013 by Christian Elliott Comments Off

I’m at the Alzheimer’s Association International Conference (AAIC) in Boston this week, and one of the most discussed topics is the power of brain imaging tests to detect amyloid beta protein in the brain, one of the main hallmarks of Alzheimer’s disease pathology. Positron Emission Tomography (PET) imaging tests can identify amyloid beta deposits in […]

New Progress on a Blood Test for Alzheimer’s Disease

2nd July 2012 by Christian Elliott Comments Off

The PLoS ONE science journal published an interesting study performed by the Brain and Aging Research Program at the University of New South Wales in Sydney, Australia. The study sampled apolipoprotein levels in blood samples from over 600 older adults participating in the ongoing Sydney Memory and Aging Study. Apolipoproteins are proteins that transport cholesterol […]

The Pros and Cons of Amyvid for Amyloid Beta Imaging

25th June 2012 by Christian Elliott Comments Off

A topic that received a lot of attention at the University of California San Diego School of Medicine update on Alzheimer’s research was the use of Eli Lilly’s Amyvid for detection of amyloid beta deposits in the brain, one of the physical signatures of Alzheimer’s Disease. Dr. Gil Rabinovici, MD, a physician and researcher at […]