Tag Archives: Alzheimer’s Test

Using Blood Protein Markers for Brain Health Screening

Can a simple blood test be possible to screen for Alzheimer’s disease and other brain conditions? New research discussed at the Alzheimer’s Association International Conference (AAIC) last month suggests that reliable, low cost blood serum analysis for brain biomarkers is a possibility within the next decade or so. Blood tests are an attractive screening option […]

Should Medicare Cover the Cost of Brain Imaging Tests for Alzheimer’s Diagnosis?

I’m at the Alzheimer’s Association International Conference (AAIC) in Boston this week, and one of the most discussed topics is the power of brain imaging tests to detect amyloid beta protein in the brain, one of the main hallmarks of Alzheimer’s disease pathology. Positron Emission Tomography (PET) imaging tests can identify amyloid beta deposits in […]

Another Alzheimer’s Drug Candidate Bites the Dust

Add Baxter International’s Gammagard to the ash heap of failed Alzheimer’s drug candidates. Baxter announced today that Gammagard did not provide any cognitive or functional improvement in 390 patients with mild to moderate Alzheimer’s disease. The patients who were enrolled in the Phase III trial received the drug through infusions over an 18 month period. […]

The Coming Ethical Quagmire with Brain Imaging Tests

With sophisticated brain imaging tests now making their way out of research labs or clinical trials, and into the doctor’s office, both patients and physicians will have to confront some important ethical and legal questions on how these tests are used. That’s the message from a seminar on amyloid imaging, hosted by the American Academy […]

Early Detection Tests for Alzheimer’s Disease: Introduction

Rising Dementia Rates are a Global Health Trend A positive aspect of rising living standards in most of the world has been a significant improvement in worldwide average life expectancies, increasing from 52 years in 1960 to 69 years in 2009. Regional differences are even more striking — the average life expectancy for a person […]

Is the Amyloid Hypothesis Dead Wrong?

After the disaster known as bapineuzumab Phase III, I think it’s time to seriously question whether clearing amyloid beta deposits from the brain has any therapeutic benefit to Alzheimer’s patients. The bapi Phase III results speak with a resounding “No”. We are still awaiting Phase III results from Eli Lilly’s solanezumab, but the current prognosis […]

Detecting Alzheimer’s Disease 20 Years Before Symptoms Appear

A research team at Washington University School of Medicine just published the results of a study that looked at a number of cognitive changes and biomarkers that can be used to predict the risk of Alzheimer’s Disease long before symptoms appear – in some cases up to 20 years before symptom onset. The study, published […]

New Progress on a Blood Test for Alzheimer’s Disease

The PLoS ONE science journal published an interesting study performed by the Brain and Aging Research Program at the University of New South Wales in Sydney, Australia. The study sampled apolipoprotein levels in blood samples from over 600 older adults participating in the ongoing Sydney Memory and Aging Study. Apolipoproteins are proteins that transport cholesterol […]